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Unleashing Cognitive Power: The Niacinamide Advantage

June 02, 2023 5 min read

Niacinamide and Cognitive Function

Niacinamide, also known as Vitamin B3, is a powerful nutrient that has captured the attention of health enthusiasts and biohackers alike. This powerful vitamin has been recognized for its role in promoting cognitive function and overall brain health.

Niacinamide: What It Is and How It Works

Niacinamide is a form of vitamin B3, an essential nutrient that supports many cellular processes in your body. It plays a significant role in energy production, DNA repair, and maintaining the health of your skin and brain.

Being water-soluble, it is not stored in your body and hence, needs to be replenished regularly. A diet deficient in niacin can lead to pellagra, a condition characterized by diarrhea, dementia, and dermatitis.

The Role of Niacinamide in Cognitive Function

The potential of niacinamide in supporting and enhancing cognitive function is underpinned by a growing body of research. From supporting energy production in brain cells to mitigating cognitive decline, the benefits of this essential vitamin are far-reaching and impactful.

Boosts Brain Energy

The brain is a high-energy organ, making up about 2% of a person's weight but consuming around 20% of the body's energy. Niacinamide plays a crucial role in this energy metabolism. It is a vital component in the production of Nicotinamide Adenine Dinucleotide (NAD+), a coenzyme found in all living cells and crucial for energy metabolism. NAD+ is used by our brain cells (neurons) to convert the food we eat into the energy they need to perform their functions. This process, known as cellular respiration, is essential to maintaining healthy brain function and cognition.

Protects Neurons

Beyond its role in energy production, niacinamide provides neuroprotective benefits. It aids in the protection and repair of neurons, the working unit of the brain. This is particularly important as damage to neurons can lead to neurodegenerative diseases such as Alzheimer's and Parkinson's. Research shows that niacinamide can increase the production of brain-derived neurotrophic factor (BDNF), a protein that supports the survival of existing neurons and encourages the growth and differentiation of new neurons and synapses.

Enhances Memory

Memory function and cognitive flexibility are also areas where niacinamide can play a role. Cognitive flexibility is the mental ability to switch between thinking about two different concepts and to think about multiple concepts simultaneously. Some research suggests that niacinamide may improve these cognitive processes. It appears to boost spatial memory – the memory responsible for the recording of information about one's environment and spatial orientation.

On top of these benefits, some studies have suggested that niacinamide has the potential to enhance attention and inhibit inflammatory processes in the brain, which could be useful in conditions like ADHD and multiple sclerosis, respectively.

Our previous article, Biohacker's Guide to Cognitive Function, provides a more comprehensive guide on various ways to enhance your mental prowess. It's always best to approach cognitive enhancement from multiple angles, making niacinamide just one piece of your overall brain health strategy.

Integrating Niacinamide Into Your Biohacking Routine

Niacinamide can be incorporated into your daily routine in several ways.

  1. Diet: Many foods are rich in vitamin B3. Including these in your diet can help boost your niacinamide levels.

  2. Supplements: Niacinamide supplements are a convenient way to ensure that you are getting enough of this vital nutrient. Our NAD Regen is a perfect example.

  3. Lifestyle Habits: Regular exercise, adequate sleep, and stress management can enhance the benefits of niacinamide.

It is crucial to note that niacinamide is not a magic pill. Instead, it is a tool that can be used in conjunction with other biohacking supplements and healthy lifestyle habits.

Diet: Boost Your Niacinamide Intake Naturally

Many foods are rich in vitamin B3, also known as niacinamide. By incorporating these nutrient-dense choices into your daily meals, you can naturally increase your vitamin B3 levels.

Here are five nutritious foods that are perfect for biohacking and packed with niacinamide:

  1. Chicken Breast: Lean meats, such as chicken breast, are an excellent source of niacinamide. A 3-ounce serving of chicken can provide almost 60% of the daily recommended intake.

  2. Tuna: This popular fish is not only rich in omega-3 fatty acids but also boasts a high niacinamide content. Just one can of tuna can provide about 80% of the recommended daily intake.

  3. Brown Rice: A great option for those following a plant-based diet. A cup of cooked brown rice can provide around 19% of the daily niacinamide requirement.

  4. Mushrooms: Particularly, portobello mushrooms are packed with niacinamide. A cup of grilled portobello mushroom caps can provide about 30% of the daily recommended intake.

  5. Green Peas: This humble vegetable is a good source of several vitamins including B3. A cup of green peas can provide about 20% of your daily niacinamide needs.

In addition to these foods, you can also boost your niacinamide levels by taking high-quality supplements. More on that in a moment!

Remember, it's not just about incorporating these foods into your diet but making sure that they are part of a balanced, whole-foods diet. Visit our post on 3 Foods Perfect for Biohacking for more information.

Niacinamide Supplements: Ensuring Sufficient Intake

While a balanced diet can provide adequate amounts of niacinamide for most people, there may be circumstances where an individual's requirements exceed what can be easily achieved through diet alone. This is where niacinamide supplements come in.

Niacinamide supplements are a convenient and effective way to ensure you're getting sufficient amounts of this vital nutrient. They're available in various forms, including capsules, tablets, and powders, and can be found in different strengths, typically ranging from 150 mg to 500 mg per serving. However, it's important to note that the source of niacinamide matters as much as, if not more than the quantity per serving

A fascinating development in the realm of niacinamide supplementation is the advent of different niacinamide variants designed to provide specific benefits or target certain pathways. One such variant is Cuprous Niacin.

Cuprous Niacin: The New Face of Niacinamide

NAD Regen with Niacinamide, NAD3, Spermidine and resveratrol

Cuprous Niacin is a newer form of niacinamide that combines the benefits of traditional niacinamide with the power of copper. The resulting compound has a unique structure that allows it to donate electrons directly to cellular pathways, essentially helping to "jump-start" cellular processes and potentially offering enhanced benefits over standard niacinamide.

Specifically, Cuprous Niacin is designed to support the production of superoxide dismutase (SOD), one of the body's most potent antioxidant enzymes. SOD plays a critical role in protecting against oxidative stress, a key factor in aging and various diseases, including neurodegenerative diseases.

A perfect example of a high-quality niacinamide supplement is our own NAD Regen. Formulated for optimal bioavailability, it ensures that your body gets the most benefit from every dose. NADRegen combines the power of niacinamide with other supportive nutrients to provide a comprehensive approach to cellular health and cognitive function.

Supplementation can be an effective strategy to complement your diet and lifestyle, ensuring you're getting the most out of your biohacking efforts.

Remember, Everyone is Unique

Like all things related to health and wellness, responses to niacinamide can vary between individuals. This concept is called bio-individuality, which means that there is no one-size-fits-all approach to nutrition and health.

Are you interested in optimizing your cognitive function and overall health? Start your biohacking journey today.