NMN Supplements: What Do the Studies Say?

Learn what researchers have uncovered in their quest to understand the effects NMN supplements may have on health, disease, and longevity. 

- Heather Eastman, NSCA-CPT, CF L1

NAD+ (nicotinamide adenine dinucleotide) is a compound found in all living cells and plays a critical role in DNA repair and cellular metabolism. Initial research has shown NMN supplements and other NAD+ intermediates have therapeutic and preventative potential regarding age-related degeneration and disease. 

What Do NMN Supplements Do?

As discussed in the BioStack Labs Official Supplementation Protocol, NAD+ helps with the repair and boosting of metabolic functions within every cell in your body. Several studies show consistent NMN supplementation enhances NAD+ synthesis in a variety of tissues, including the skeletal muscles and various organs. 

It has also been demonstrated that long-term administration (over 1 year) of NMN is safe, non-toxic, and can potentially mitigate the effects of age-related physiological decline. NMN supplements do this by suppressing age-related adipose tissue inflammation and improving insulin sensitivity, a major factor in the development ofcardiovascular disease and type 2 diabetes. 

NMN supplementation has also been shown to improve mitochondrial function in skeletal and cardiac muscle, as well as in the liver. By increasing energy expenditure throughout the body, this may contribute to natural weight loss in addition to improving cellular metabolism and promoting healthy ageing. 

What does this mean for us? When NAD+ is present at optimal levels, cells are able to neutralize free radicals and function at their best. The result is more energy, reduced signs of aging, optimal performance, and lower risk of developing disease.

Who Can benefit from NMN supplements?

As we age, our NAD+ levels naturally decline, but there are several factors that can accelerate this process, including stress, poor diet, alcohol consumption, lack of sleep, and exposure to harmful UV rays and pollution. Some of these factors are within our control, and some are not, which is why research into mitigating NAD+ decline and even restoring optimal levels through supplementation and biohacking has grown in popularity in recent years. 

Perhaps most interesting to come out of the research is that older subjects seem to respond better to NMN supplementation than their younger counterparts. This may be because the age-related depletion of NAD+ in the body makes older subjects more sensitive to replenishment using NMN supplements. This is promising news for anyone starting their anti-aging journey later in life. 

Just like planting a tree, the best time to start an anti-aging protocol is 20 years ago, and the second-best time is right now. As mentioned in the post What is the Best Age to Start Biohacking, those aged 40 and above would see the biggest benefits from adopting biohacking strategies like taking a daily NMN supplement.

What’s the Best NMN Supplement Protocol?

Anti-aging experts have understood the importance of NMN supplementation for years. Dr. David Sinclair, professor of genetics and co-director of the Paul F. Glenn Center for Biology and Aging Research at Harvard Medical School, follows a strict daily supplement protocol that includes NMN and Resveratrol every morning.

Our flagship biohacking supplement, NAD Regen, contains 300mg of NMN per serving and 200mg of Resveratrol, as well as over 500 mg of Liposomal Vitamin C and several other powerful antioxidants. NAD Regen and its sister product, Cell Shield, were formulated with ingredients that work synergistically to deliver the best possible health-boosting and anti-aging effects for the lowest dosage. 

Since it takes consistent daily supplementation to build up and maintain optimal levels of NAD+, this supplement stack is available as a subscription to help customers achieve and maintain results. For more information on this and other biohacking recommendations, check out 5 Free Daily Biohacks We Recommend. 

Learn more about NAD Regen and Cell Shield here.